In its original concept, vaccination aims to mimic the development of naturally acquired immunity by inoculation of nonpathogenic but still immunogenic components of the pathogen in question, or closely related organisms. The term “vaccine” (from the Latin term “vacca,” meaning cow) was first coined by Edward Jenner to describe the inoculation of humans with the cowpox virus to confer protection against the related human smallpox virus and illustrates the close relationship between human and animal infectious disease sciences.
While veterinary vaccines comprise only approximately 23% of the global market for animal health products, the sector has grown consistently due mainly to new technological advances in vaccine development, the continuous development of drug resistance by pathogens, and the emergence of new diseases
Veterinary Vaccines
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Vaccine Design
Reduce unnecessary use of antimicrobials in livestock production and aquaculture.
There are circumstances where antibiotics are required in agriculture and aquaculture – to maintain animal welfare and food security. However, much of their global use is not for treating sick animals, but rather to prevent infections or simply to promote growth. The quantity of antibiotics used in livestock is vast. In the US, for example, of the antibiotics defined as medically important for humans by the US Food and Drug Administration (FDA), over 70 percent (by weight) are sold for use in animals. Many countries are also likely to use more antibiotics in agriculture than in humans but they do not even hold or publish the information. The majority of scientists see this as a threat to human health, given that wide-scale use of antibiotics encourages the development of resistance, which can spread to affect humans and animals alike.
Vaccines can prevent infections and therefore lower the demand for therapeutic treatments, reducing use of antimicrobials and so slowing the rise of drug resistance.
Our focus is to harness structure-based design, or structural vaccinology to support the emerging demand for veterinary vaccines.
Benefits of Vaccines
Sustainable livestock and aqucultre production
Subunit vaccines are part of the emerging new generation of veterinary vaccines, which offer significant benefits when combined with plant based production system.
- In-silico design of potential subunit vaccines exploits state of art bioinformatics
- Use f heterologous expression system enhancing overal safety ---non infectious
- Leaf production system offer flexibility with low capital costs
- prodcuig vaccine directly ina background that can become an ingredient ina feed formulation
- opportunity of oral administration of vaccine
Advantages of subunit vaccines
